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PreviewIssue DateTitleAuthor(s)
2016Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signalingBroughton, S.E.; Hercus, T.R.; Nero, T.L.; King-Scott, J.; Lopez, A.F.; Parker, M.W.; Dottore, M.; McClure, B.J.; Dhagat, U.; Taing, H.; Gorman, M.A.
2017Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signallingHughes, J.; Dawson, R.; Tea, M.; McAninch, D.; Piltz, S.; Jackson, D.; Stewart, L.; Ricos, M.; Dibbens, L.; Harvey, N.; Thomas, P.
2012CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesisPan, W.; Pham, V.; Stratman, A.; Castranova, D.; Kamei, M.; Kidd, K.; Lo, B.; Shaw, K.; Torres-Vazquez, J.; Mikelis, C.; Gutkind, J.; Davis, G.; Weinstein, B.
2011Regulation of progesterone receptor activity by cyclin dependent kinases 1 and 2 occurs in part by phosphorylation of the SRC-1 carboxyl-terminusMoore, N.; Weigel, N.
2015Novel IL1RAPL1 mutations associated with intellectual disability impair synaptogenesisRamos-Brossier, M.; Montani, C.; Lebrun, N.; Gritti, L.; Martin, C.; Seminatore-Nole, C.; Toussaint, A.; Moreno, S.; Poirier, K.; Dorseuil, O.; Chelly, J.; Hackett, A.; Gecz, J.; Bieth, E.; Faudet, A.; Heron, D.; Kooy, R.; Loeys, B.; Humeau, Y.; Sala, C.; et al.
2014Leptin mediates the increase in blood pressure associated with obesitySimonds, S.; Pryor, J.; Ravussin, E.; Greenway, F.; Dileone, R.; Allen, A.; Bassi, J.; Elmquist, J.; Keogh, J.; Henning, E.; Myers, M.; Licinio, J.; Brown, R.; Enriori, P.; O’Rahilly, S.; Sternson, S.; Grove, K.; Spanswick, D.; Farooqi, I.; Cowley, M.
2016Mutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsyRicos, M.G.; Hodgson, B.L.; Pippucci, T.; Saidin, A.; Ong, Y.S.; Heron, S.E.; Licchetta, L.; Bisulli, F.; Bayly, M.A.; Hughes, J.; Baldassari, S.; Palombo, F.; Epilepsy Electroclinical Study Group,; Santucci, M.; Meletti, S.; Berkovic, S.F.; Rubboli, G.; Thomas, P.Q.; Scheffer, I.E.; Tinuper, P.; et al.
2015p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migrationTurvey, M.; Klingler-Hoffmann, M.; Hoffmann, P.; McColl, S.
2013The genomic landscape of hypodiploid acute lymphoblastic leukemiaTo, L.
2013Identification Of KLHL41 mutations implicates BTB-Kelch-Mediated Ubiquitination as an alternate pathway to myofibrillar disruption in nemaline myopathyGupta, V.; Ravenscroft, G.; Shaheen, R.; Todd, E.; Swanson, L.; Shiina, M.; Ogata, K.; Hsu, C.; Clarke, N.; Darras, B.; Farrar, M.; Hashem, A.; Manton, N.; Muntoni, F.; North, K.; Sandaradura, S.; Nishino, I.; Hayashi, Y.; Sewry, C.; Thompson, E.; et al.