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Results 1-10 of 11 (Search time: 0.002 seconds).
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PreviewIssue DateTitleAuthor(s)
2006Hydralazine inhibits rapid acrolein-induced protein oligomerization: Role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotectionBurcham, P.; Pyke, S.
2004Protein adduct-trapping by hydrazinophthalazine drugs: Mechanisms of cytoprotection against acrolein-mediated toxicityBurcham, P.; Fontaine, F.; Kaminskas, L.; Petersen, D.; Pyke, S.
2003Cylindrospermopsin-induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytesFroscio, S.; Humpage, A.; Burcham, P.; Falconer, I.
2004Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehydeKaminskas, L.; Pyke, S.; Burcham, P.
2005Cylindrospermopsin genotoxicity and cytotoxicity: Role of cytochrome P-450 and oxidative stressHumpage, A.; Fontaine, F.; Froscio, S.; Burcham, P.; Falconer, I.
2004Optimisation of the comet genotoxicity assay in freshly isolated murine hepatocytes: detection of strong in vitro DNA damaging properties for styreneFontaine, F.; DeGraaf, Y.; Ghaoui, R.; Sallustio, B.; Edwards, J.; Burcham, P.
2003Reactivity with tris(hydroxymethyl)aminomethane confounds immunodetection of acrolein-adducted proteinsBurcham, P.; Fontaine, F.; Petersen, D.; Pyke, S.
2005Differences in lysine adduction by acrolein and methyl vinyl ketone: Implications for cytotoxicity in cultured hepatocytesKaminskas, L.; Pyke, S.; Burcham, P.
2003UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytesGhaoui, R.; Sallustio, B.; Burcham, P.; Fontaine, F.
2004Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in miceKaminskas, L.; Pyke, S.; Burcham, P.

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