Adelaide Research & Scholarship
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https://hdl.handle.net/2440/102782
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| Type: | Journal article |
| Title: | Metal–organic framework coatings as cytoprotective exoskeletons for living cells |
| Author: | Liang, K. Richardson, J. Cui, J. Caruso, F. Doonan, C. Falcaro, P. |
| Citation: | Advanced Materials, 2016; 28(36):7910-7914 |
| Publisher: | Wiley |
| Issue Date: | 2016 |
| ISSN: | 0935-9648 1521-4095 |
| Statement of Responsibility: | Kang Liang, Joseph J. Richardson, Jiwei Cui, Frank Caruso, Christian J. Doonan and Paolo Falcaro |
| Abstract: | The biomimetic mineralization of metal–organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal. |
| Keywords: | Saccharomyces cerevisiae Protective Agents Crystallization Cell Division Cell Survival Cytoprotection Biomimetic Materials Metal-Organic Frameworks |
| Rights: | © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
| DOI: | 10.1002/adma.201602335 |
| Grant ID: | http://purl.org/au-research/grants/arc/CE140100036 |
| Published version: | http://dx.doi.org/10.1002/adma.201602335 |
| Appears in Collections: | Aurora harvest 3 Chemistry and Physics publications |
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