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https://hdl.handle.net/2440/104026
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Type: | Journal article |
Title: | The mediterranean diet and cognitive function among healthy older adults in a 6-month randomised controlled trial: the MedLey study |
Author: | Knight, A. Bryan, J. Wilson, C. Hodgson, J.M. Davis, C.R. Murphy, K.J. |
Citation: | Nutrients, 2016; 8(9):579-1-579-17 |
Publisher: | MDPI AG |
Issue Date: | 2016 |
ISSN: | 2072-6643 2072-6643 |
Statement of Responsibility: | Alissa Knight, Janet Bryan, Carlene Wilson, Jonathan M. Hodgson, Courtney R. Davis and Karen J. Murphy |
Abstract: | Evidence from a limited number of randomised controlled intervention trials (RCTs) have shown that a Mediterranean dietary pattern may reduce the risk of cognitive decline and enhance cognitive function among healthy older adults. However, there are currently no data in non-Mediterranean older adult populations. The present study aimed to address this gap by examining the effect of a Mediterranean dietary pattern (MedDiet) for six months on aspects of cognitive function in a randomised controlled intervention trial (the MedLey study) that extended for a duration of 18 months. In the final analysed cohort, a total of 137 men and women (mean age of 72.1 ± 5.0 years) randomly assigned to either a MedDiet or control diet (HabDiet) (i.e., habitual dietary intake), were assessed on a comprehensive neuropsychological test battery, including 11 individual tests. In multivariable-adjusted models, the MedDiet group did not perform significantly better than the HabDiet control group for executive functioning (adjusted mean differences: +2.53, 95% CI −2.59 to 7.65, p = 0.33); speed of processing (adjusted mean differences: +3.24, 95% CI −1.21 to 7.70, p = 0.15); memory (adjusted mean differences: +2.00, 95% CI −3.88 to 7.88, p = 0.50); visual-spatial ability (adjusted mean differences: +0.21, 95% CI −0.38 to 0.81, 0.48); and overall age-related cognitive performance (adjusted mean differences: +7.99, 95% CI −4.00 to 19.9, p = 0.19). In conclusion, this study did not find evidence of a beneficial effect of a MedDiet intervention on cognitive function among healthy older adults. |
Keywords: | Mediterranean diet; cognitive function; randomised controlled trial; older adults |
Rights: | © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
DOI: | 10.3390/nu8090579 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1050949 |
Published version: | http://dx.doi.org/10.3390/nu8090579 |
Appears in Collections: | Aurora harvest 3 Psychology publications |
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hdl_104026.pdf | Published version | 505.82 kB | Adobe PDF | View/Open |
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