Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/10619
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Central nervous system imaging in Crouzon Syndrome |
Author: | Proudman, T. Clark, B. Moore, M. Abbott, A. David, D. |
Citation: | Journal of Craniofacial Surgery, 1995; 6(5):401-405 |
Publisher: | LITTLE BROWN CO |
Issue Date: | 1995 |
ISSN: | 1049-2275 1536-3732 |
Abstract: | Although the need to prevent the secondary effects of craniosynostosis on the central nervous system is fundamental to the practice of craniofacial surgery, the detailed structural anatomy of the central nervous system in the syndromal craniosynostoses has become the subject of recent interest. A clinical and radiographic review of a population of 59 patients with Crouzon's syndrome determined the frequency of central nervous system deformities. Twelve percent of patients had evidence of decreased mental function. Ventriculomegaly on computed tomographic scan was present in 51% and found to be of three grades: mild, moderate, and severe (hydrocephalus). This was nonprogressive in 7 of the 11 patients with follow-up computed tomographic scans. Ten patients underwent surgical release to increase intracranial space; however, 6 of these patients showed no progression in ventricular size. Nonventricular anomalies were found less frequently (14%). Central nervous system findings show fewer nonventricular anomalies than in Apert's syndrome patients, with a corresponding higher mental function. The principal anomaly of ventriculomegaly is not directly related to suture defect and may represent a primary brain abnormality. Recommendations are made for the assessment and management of patients with Crouzon's syndrome with reference to these areas. |
Keywords: | Brain Cerebral Ventricles Humans Craniofacial Dysostosis Tomography, X-Ray Computed Magnetic Resonance Imaging Cerebral Ventriculography Adolescent Adult Child Child, Preschool Infant Infant, Newborn Female Male |
DOI: | 10.1097/00001665-199509000-00016 |
Published version: | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=ovft&AN=00001665-199509000-00016&PDF=y |
Appears in Collections: | Aurora harvest 2 Surgery publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.