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https://hdl.handle.net/2440/10689
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Type: | Journal article |
Title: | Intraoperative imprint cytologic assessment of the sentinel node for early breast cancer |
Author: | Bochner, M. Farshid, G. Dodd, T. Kollias, J. Gill, P. |
Citation: | World Journal of Surgery, 2003; 27(4):430-432 |
Publisher: | Springer |
Issue Date: | 2003 |
ISSN: | 0364-2313 1432-2323 |
Statement of Responsibility: | Melissa A. Bochner, Gelareh Farshid, Thomas J. Dodd, James Kollias and P. Grantley Gill |
Abstract: | An increasing number of patients are undergoing sentinel node biopsy alone for axillary staging of early breast cancer. A reliable method for evaluating the status of the sentinel node intraoperatively would allow patients with sentinel node metastases to undergo immediate rather than delayed axillary clearance. Sentinel nodes in 53 consecutive patients were examined by intraoperative imprint cytology. When compared with subsequent analysis by hematoxylin-eosin staining and immunohistochemistry, the accuracy of imprint cytology for the detecting nodal metastases was 81.1%; the false negative rate was 47.0%, and there were no false positives. Results were made available to the operating surgeon within a mean time of 25 minutes. All but one of the false negatives involved micrometastatic deposits of less than 0.1 mm. Intraoperative imprint cytologic examination of the sentinel node is a useful technique that can be performed efficiently and without loss of nodal tissue for subsequent analysis. With the use of this technique, more than 50% of lymph node-positive patients would potentially be spared a second operation. |
Keywords: | Axilla Humans Breast Neoplasms Sentinel Lymph Node Biopsy Intraoperative Period Adult Aged Aged, 80 and over Middle Aged Female |
DOI: | 10.1007/s00268-002-6721-x |
Published version: | http://dx.doi.org/10.1007/s00268-002-6721-x |
Appears in Collections: | Aurora harvest 2 Surgery publications |
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