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Results 11-20 of 30 (Search time: 0.001 seconds).
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PreviewIssue DateTitleAuthor(s)
2013Post-translational regulation of sphingosine kinasesChan, H.; Pitson, S.
2012Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: functional differences between sphingosine kinase 1a and 1bLim, K.; Tonelli, F.; Berdyshev, E.; Gorshkova, I.; Leclercq, T.; Pitson, S.; Bittman, R.; Pyne, S.; Pyne, N.
2010Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their functionWoodcock, J.; Ma, Y.; Coolen, C.; Pham, D.; Jones, C.; Lopez, A.; Pitson, S.
2010FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cellsTonelli, F.; Lim, K.; Loveridge, C.; Long, J.; Pitson, S.; Tigyi, G.; Bittman, R.; Pyne, S.; Pyne, N.
2011A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1Pitman, M.; Barr, R.; Gliddon, B.; Magarey, A.; Moretti, P.; Pitson, S.
2010The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian CellsTonelli, F.; Loveridge, C.; Leclercq, T.; Lim, K.; Long, J.; Berdyshev, E.; Tate, R.; Natarajan, V.; Pitson, S.; Pyne, N.; Pyne, S.
2010Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1Jarman, K.; Moretti, P.; Zebol, J.; Pitson, S.
2011The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1a protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6Pchejetski, D.; Nunes, J.; Coughlan, K.; Lall, H.; Pitson, S.; Waxman, J.; Sumbayev, V.
2011Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesisLeclercq, T.; Moretti, P.; Pitson, S.
2011Tumour necrosis factor alpha (TNF-α) stimulation of cells with established dengue virus type 2 infection induces cell death that is accompanied by a reduced ability of TNF-α to activate nuclear factor κB and reduced sphingosine kinase-1 activityWati, S.; Rawlinson, S.; Ivanov, R.; Dorstyn, L.; Beard, M.; Jans, D.; Pitson, S.; Burrell, C.; Li, P.; Carr, J.