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PreviewIssue DateTitleAuthor(s)
2009Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cellsBacker, J.; Krivoshein, A.; Hamby, C.; Pizzonia, J.; Gilbert, K.; Ray, Y.; Brand, H.; Paton, A.; Paton, J.; Backer, M.
2014Preconditioning with endoplasmic reticulum stress ameliorates endothelial cell inflammationLeonard, A.; Paton, A.; El-Quadi, M.; Paton, J.; Fazal, F.; Komarova, Y.
2009Activation of the Akt-NF-kappa B Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein ResponseYamazaki, H.; Hiramatsu, K.; Hayakawa, K.; Tagawa, Y.; Okamura, M.; Ogata, R.; Huang, T.; Nakajima, S.; Yao, J.; Paton, A.; Paton, J.; Kitamura, M.
2015Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatmentAdomako, A.; Calvo, V.; Biran, N.; Osman, K.; Chari, A.; Paton, J.; Paton, A.; Moore, K.; Schewe, D.; Aguirre-Ghiso, J.
2013ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein responseHeijmans, J.; van Lidth de Jeude, J.; Koo, B.; Rosekrans, S.; Wielenga, M.; van de Wetering, M.; Ferrante, M.; Lee, A.; Onderwater, J.; Paton, J.; Paton, A.; Mommaas, A.; Kodach, L.; Hardwick, J.; Hommes, D.; Clevers, H.; Muncan, V.; van den Brink, G.
2008Decreased ER-associated degradation of alpha-TCR induced by Grp78 depletion with the SubAB cytotoxinLass, A.; Kujawa, M.; McConnell, E.; Paton, A.; Paton, J.; Wojcik, C.
2012BiP prevents rod opsin aggregationAthanasiou, D.; Kosmaoglou, M.; Kanuga, N.; Novoselov, S.; Paton, A.; Paton, J.; Chapple, J.; Cheetham, M.; Brodsky, J.L.
2010Tissue factor-dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by shiga toxigenic Escherichia coliWang, H.; Paton, J.; Thorpe, C.; Bonder, C.; Sun, W.; Paton, A.
2006AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiPPaton, A.; Beddoe, T.; Thorpe, C.; Whisstock, J.; Wilce, M.; Rossjohn, J.; Talbot, U.; Paton, J.
2008Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB(5) toxin that targets the endoplasmic reticulum chaperone BiPChong, D.; Paton, J.; Thorpe, C.; Paton, A.