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https://hdl.handle.net/2440/117350
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dc.contributor.author | Pham, C. | - |
dc.contributor.author | Karnon, J. | - |
dc.contributor.author | Norman, R. | - |
dc.contributor.author | Mol, B. | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Reproductive Biomedicine Online, 2018; 37(5):555-563 | - |
dc.identifier.issn | 1472-6483 | - |
dc.identifier.issn | 1472-6491 | - |
dc.identifier.uri | http://hdl.handle.net/2440/117350 | - |
dc.description.abstract | Research Question: Does delaying IVF for 6 months in couples with unexplained infertility, compared with immediate IVF treatment, decrease the cost of IVF without compromising success rates? Design: Decision modelling was used to evaluate the cost and outcomes of immediate IVF versus delayed IVF for a cohort of women aged <40 years suffering unexplained infertility. Australian data and costs were used in the analysis. For different age groups, three scenarios were tested where 10%, 50% and 90% of couples with unexplained infertility delayed IVF for 6 months if they had a good prognosis for natural conception. The study included a total of 8781 couples aged <40 years, diagnosed with unexplained infertility and who had IVF in 2013. Results: The studied couples underwent 27,648 fresh and frozen embryo transfers, for an estimated total cost of $141 million. Potential out-of-pocket cost savings if 90% of couples delayed IVF ranged from $4.7 to $12.2 million, with Medicare cost savings of up to $15.1 million. The impact on the total pregnancy and live birth rates after 18 months was minimal. Conclusions: In couples with unexplained infertility and a good prognosis for natural conception, delaying IVF for 6 months could substantially decrease out-of-pocket costs without compromising pregnancy and live birth rates over an 18-month period. | - |
dc.description.statementofresponsibility | Clarabelle T Pham, Jonathan D Karnon, Robert J Norman, Ben W Mol | - |
dc.language.iso | en | - |
dc.publisher | Elsevier | - |
dc.rights | © 2018 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.rbmo.2018.08.024 | - |
dc.subject | Costs and cost analysis; decision trees; IVF, live birth; pregnancy; unexplained infertility | - |
dc.title | Cost-effectiveness modelling of IVF in couples with unexplained infertility | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.rbmo.2018.08.024 | - |
dc.relation.grant | http://purl.org/au-research/grants/nhmrc/1082548 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Pham, C. [0000-0003-4509-5368] | - |
dc.identifier.orcid | Karnon, J. [0000-0003-3220-2099] | - |
dc.identifier.orcid | Norman, R. [0000-0002-3118-3896] | - |
dc.identifier.orcid | Mol, B. [0000-0001-8337-550X] | - |
Appears in Collections: | Aurora harvest 3 Public Health publications |
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