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https://hdl.handle.net/2440/124836
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Type: | Journal article |
Title: | Neutrophil-lymphocyte ratio - a simple, accessible measure of inflammation, morbidity and prognosis in psychiatric disorders? |
Author: | Zulfic, Z. Weickert, C.S. Weickert, T.W. Liu, D. Myles, N. Galletly, C. |
Citation: | Australasian Psychiatry, 2020; 28(4):454-458 |
Publisher: | SAGE Publications |
Issue Date: | 2020 |
ISSN: | 1039-8562 1440-1665 |
Statement of Responsibility: | Zlatan Zulfic, Cynthia Shannon Weickert, Thomas W Weickert, Dennis Liu, Nicholas Myles, Cherrie Galletly |
Abstract: | OBJECTIVE: A narrative review to describe the utility of the neutrophil-lymphocyte ratio (NLR) as an inflammatory marker in psychiatric and non-psychiatric disorders and to discuss the potential role of NLR in psychiatric research. CONCLUSIONS: NLR is inexpensive and readily available using division of two measures obtained on routine blood testing. NLR is elevated in a number of psychiatric disorders. It can predict morbidity and mortality in a wide range of non-psychiatric conditions, but this has not been confirmed in psychiatric conditions. It can be calculated in large, pre-existing datasets to investigate clinical correlates of inflammatory processes. NLR may have a future role in identifying patients with an inflammatory phenotype who could benefit from adjunctive anti-inflammatory medications. |
Keywords: | neutrophil–lymphocyte ratio inflammatory marker morbidity psychiatric disorders prognosis |
Rights: | © The Royal Australian and New Zealand College of Psychiatrists 2020 |
DOI: | 10.1177/1039856220908172 |
Published version: | http://dx.doi.org/10.1177/1039856220908172 |
Appears in Collections: | Aurora harvest 4 Psychiatry publications |
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