Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/132091
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Book chapter |
Title: | Pharmacotherapies for cannabis use disorders: Clinical challenges and promising therapeutic agents |
Author: | Nielsen, S. Sabioni, P. Gowing, L. Le Foll, B. |
Citation: | Substance Use Disorders: From Etiology to Treatment, 2020 / Nadar, M.A., Hurd, Y.L. (ed./s), vol.258, Ch.13, pp.355-372 |
Publisher: | Springer |
Publisher Place: | Cham, Switzerland |
Issue Date: | 2020 |
Series/Report no.: | Handbook of Experimental Pharmacology; 258 |
ISBN: | 3030336786 9783030336783 |
Editor: | Nadar, M.A. Hurd, Y.L. |
Statement of Responsibility: | Suzanne Nielsen, Pamela Sabioni, Linda Gowing, and Bernard Le Foll |
Abstract: | This chapter reviews pharmacotherapies that have been trialled for cannabis dependence, identifying those that warrant further research and those of little or uncertain value. A diverse range of medicines have been tested, representing a broad range of pharmacological strategies. These include tetrahydrocannabinol preparations, various types of antidepressant, anxiolytics, a glutamatergic modulator and the neuropeptide oxytocin. Cannabinoid agonists warrant further research. For the FAAH inhibitor PF-04457845, oxytocin, varenicline and gabapentin, although there is a signal to indicate further research is warranted, these medications do not yet have sufficient evidence to support clinical use, and larger, longer-term trials are needed in representative treatment-seeking populations. Special populations that warrant consideration are those with cannabis dependence and concurrent mental health conditions and those that develop dependence through therapeutic use. |
Keywords: | Cannabis; Cannabis dependence; Cannabis use disorder; Pharmacotherapy; Treatment |
Rights: | © Springer Nature Switzerland AG 2019 |
DOI: | 10.1007/164_2019_258 |
Published version: | https://link.springer.com/book/10.1007/978-3-030-33679-0 |
Appears in Collections: | Aurora harvest 4 Pharmacology publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.