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https://hdl.handle.net/2440/134108
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Type: | Journal article |
Title: | Phases of reprogramming |
Author: | David, L. Polo, J.M. |
Citation: | Stem Cell Research, 2014; 12(3):754-761 |
Publisher: | Elsevier |
Issue Date: | 2014 |
ISSN: | 1873-5061 1876-7753 |
Statement of Responsibility: | Laurent David, Jose M. Polo |
Abstract: | Despite advances in the field of somatic cell reprogramming, an understanding and exploration of the underlying mechanisms governing this process are only recently emerging. It is now increasingly apparent that key sequential events correlate with the reprogramming process; a process previously thought to be random and unpredictable is now looking, to a greater extent, defined and controlled. Herein, we will review the key cellular and molecular events associated with the reprogramming process, giving an integrative and conciliatory view of the different studies addressing the mechanism of nuclear reprogramming. |
Keywords: | Stem Cells Animals Humans Cell Differentiation Cellular Reprogramming |
Rights: | © 2014 Published by Elsevier B.V. |
DOI: | 10.1016/j.scr.2014.03.007 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1036587 ARC |
Published version: | http://dx.doi.org/10.1016/j.scr.2014.03.007 |
Appears in Collections: | Medical Sciences publications |
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