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https://hdl.handle.net/2440/135205
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Type: | Journal article |
Title: | A Comprehensive Insight Towards Pharmaceutical Aspects of Graphene Nanosheets |
Author: | Emadi, F. Emadi, A. Gholami, A. |
Citation: | Current Pharmaceutical Biotechnology, 2020; 21(11):1016-1027 |
Publisher: | Bentham Science Publishers Ltd. |
Issue Date: | 2020 |
ISSN: | 1389-2010 |
Statement of Responsibility: | Fatemeh Emadi, Arash Emadi and Ahmad Gholami |
Abstract: | Graphene Derivatives (GDs) have captured the interest and imagination of pharmaceutical scientists. This review exclusively provides pharmacokinetics and pharmacodynamics information with a particular focus on biopharmaceuticals. GDs can be used as multipurpose pharmaceutical delivery systems due to their ultra-high surface area, flexibility, and fast mobility of charge carriers. Improved effects, targeted delivery to tissues, controlled release profiles, visualization of biodistribution and clearance, and overcoming drug resistance are examples of the benefits of GDs. This review focuses on the application of GDs for the delivery of biopharmaceuticals. Also, the pharmacokinetic properties and the advantage of using GDs in pharmaceutics will be reviewed to achieve a comprehensive understanding about the GDs in pharmaceutical sciences. |
Keywords: | Graphene; pharmacokinetic; protein delivery; biopharmaceuticals; triggered release; biopharmaceutical targeting |
Rights: | © 2022 Bentham Science Publishers |
DOI: | 10.2174/1389201021666200318131422 |
Published version: | http://dx.doi.org/10.2174/1389201021666200318131422 |
Appears in Collections: | Pharmacology publications |
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