Browsing "Pharmacology" by Author Eichelbaum, M.

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PreviewIssue DateTitleAuthor(s)
2008Breast cancer risk reduction and membrane-bound catechol o-methyltransferase genetic polymorphismsJi, Y.; Olson, J.; Zhang, J.; Hildebrandt, M.; Wang, L.; Ingle, J.; Fredericksen, Z.; Sellers, T.; Miller, W.; Dixon, J.; Brauch, H.; Eichelbaum, M.; Justenhoven, C.; Hamann, U.; Ko, Y.; Bruning, T.; Chang-Claude, J.; Wang-Gohrke, S.; Schaid, D.; Weinshilboum, R.
2007Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypesSchroth, W.; Antoniadou, L.; Fritz, P.; Schwab, M.; Muerdter, T.; Zanger, U.; Simon, W.; Eichelbaum, M.; Brauch, H.
2008Clinical relevance of CYP2D6 genetics for tamoxifen response in breast cancerBrauch, H.; Schroth, W.; Eichelbaum, M.; Schwab, M.; Harbeck, N.
2010CYP2D6 polymorphisms as predictors of outcome in breast cancer patients treated with tamoxifen: Expanded polymorphism coverage improves risk stratificationSchroth, W.; Hamann, U.; Fasching, P.; Dauser, S.; Winter, S.; Eichelbaum, M.; Schwab, M.; Brauch, H.
2001Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion techniquevon Richter, O.; Greiner, B.; Fromm, M.; Fraser, R.; Omari, T.; Barclay, M.; Dent, J.; Somogyi, A.; Eichelbaum, M.
2001Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumoursColler, J.; Fritz, P.; Zanger, U.; Siegle, I.; Eichelbaum, M.; Kroemer, H.; Murdter, T.
2010Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group studyRibaudo, H.; Liu, H.; Schwab, M.; Schaeffeler, E.; Eichelbaum, M.; Motsinger-Reif, A.; Ritchie, M.; Zanger, U.; Acosta, E.; Morse, G.; Gulick, R.; Robbins, G.; Clifford, D.; Haas, D.
2007Effects of rifampicin on global gene expression in human small intestineOscarson, M.; Burk, O.; Winter, S.; Schwab, M.; Wolbold, R.; Dippon, J.; Eichelbaum, M.; Meyer, U.
2007Functional analysis of the polymorphism - 211C>T in the regulatory region of the human ABCC3 geneGradhand, U.; Tegude, H.; Burk, O.; Eichelbaum, M.; Fromm, M.; Konig, J.
2009Genetic influences on the pharmacokinetics of orally and intravenously administered Digoxin as exhibited by monozygotic twinsBirkenfeld, A.; Jordan, J.; Hofmann, U.; Busjahn, A.; Franke, G.; Kruger, N.; Igel, S.; Murdter, T.; Drescher, S.; Shi, S.; Engeli, S.; Schwab, M.; Eichelbaum, M.; Luft, F.; Fromm, M.
2008Highly multiplexed genotyping of thiopurine s-methyltransferase variants using MALDI-TOF mass spectrometry: Reliable genotyping in different ethnic groupsSchaeffeler, E.; Zanger, U.; Eichelbaum, M.; Asante-Poku, S.; Shin, J.; Schwab, M.
2004Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humansGlaeser, H.; Drescher, S.; Hofmann, U.; Heinkele, G.; Somogyi, A.; Eichelbaum, M.; Fromm, M.
2007Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated effluxIgel, S.; Drescher, S.; Murdter, T.; Hofmann, U.; Heinkele, G.; Tegude, H.; Glaeser, H.; Brenner, S.; Somogyi, A.; Omari, T.; Schafer, C.; Eichelbaum, M.; Fromm, M.
2004Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicityColler, J.; Krebsfaenger, N.; Klein, K.; Wolbold, R.; Nussler, A.; Neuhaus, P.; Zanger, U.; Eichelbaum, M.; Murdter, T.
2007Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4a: Evidence for direct regulation in the intestineTegude, H.; Schnabel, A.; Zanger, U.; Klein, K.; Eichelbaum, M.; Burk, O.
2009Pharmacogenomics of Tamoxifen TherapyBrauch, H.; Murdter, T.; Eichelbaum, M.; Schwab, M.
2007Predictive value of known and novel alleles ofCYP2B6 for efavirenz plasma concentrations in HIV-infected individualsRotger, M.; Tegude, H.; Colombo, S.; Cavassini, M.; Furrer, H.; Decosterd, L.; Blievernicht, J.; Saussele, T.; Gunthard, H.; Schwab, M.; Eichelbaum, M.; Telenti, A.; Zanger, U.
2008Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trialMorike, K.; Kivisto, K.; Schaeffeler, E.; Jagle, C.; Igel, S.; Drescher, S.; Fux, R.; Marx, C.; Hofmann, U.; Engel, C.; Wagner, F.; Delabar, U.; Meisner, C.; Bail, D.; Bohm, J.; Gleiter, C.; Ziemer, G.; Rein, J.; Hellberg, K.; Eichelbaum, M.; et al.
2010Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element bindingIstrate, M.; Nussler, A.; Eichelbaum, M.; Burk, O.
2008Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study GroupSchwab, M.; Zanger, U.; Marx, C.; Schaeffeler, E.; Klein, K.; Dippon, J.; Kerb, R.; Blievernicht, J.; Fischer, J.; Hofmann, U.; Bokemeyer, C.; Eichelbaum, M.