Showing results 10 to 29 of 33
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| Preview | Issue Date | Title | Author(s) |
| 2010 | Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study | Ribaudo, H.; Liu, H.; Schwab, M.; Schaeffeler, E.; Eichelbaum, M.; Motsinger-Reif, A.; Ritchie, M.; Zanger, U.; Acosta, E.; Morse, G.; Gulick, R.; Robbins, G.; Clifford, D.; Haas, D. |
| 2007 | Effects of rifampicin on global gene expression in human small intestine | Oscarson, M.; Burk, O.; Winter, S.; Schwab, M.; Wolbold, R.; Dippon, J.; Eichelbaum, M.; Meyer, U. |
| 2007 | Functional analysis of the polymorphism - 211C>T in the regulatory region of the human ABCC3 gene | Gradhand, U.; Tegude, H.; Burk, O.; Eichelbaum, M.; Fromm, M.; Konig, J. |
| 2009 | Genetic influences on the pharmacokinetics of orally and intravenously administered Digoxin as exhibited by monozygotic twins | Birkenfeld, A.; Jordan, J.; Hofmann, U.; Busjahn, A.; Franke, G.; Kruger, N.; Igel, S.; Murdter, T.; Drescher, S.; Shi, S.; Engeli, S.; Schwab, M.; Eichelbaum, M.; Luft, F.; Fromm, M. |
| 2008 | Highly multiplexed genotyping of thiopurine s-methyltransferase variants using MALDI-TOF mass spectrometry: Reliable genotyping in different ethnic groups | Schaeffeler, E.; Zanger, U.; Eichelbaum, M.; Asante-Poku, S.; Shin, J.; Schwab, M. |
| 2004 | Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans | Glaeser, H.; Drescher, S.; Hofmann, U.; Heinkele, G.; Somogyi, A.; Eichelbaum, M.; Fromm, M. |
| 2007 | Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux | Igel, S.; Drescher, S.; Murdter, T.; Hofmann, U.; Heinkele, G.; Tegude, H.; Glaeser, H.; Brenner, S.; Somogyi, A.; Omari, T.; Schafer, C.; Eichelbaum, M.; Fromm, M. |
| 2004 | Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity | Coller, J.; Krebsfaenger, N.; Klein, K.; Wolbold, R.; Nussler, A.; Neuhaus, P.; Zanger, U.; Eichelbaum, M.; Murdter, T. |
| 2007 | Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4a: Evidence for direct regulation in the intestine | Tegude, H.; Schnabel, A.; Zanger, U.; Klein, K.; Eichelbaum, M.; Burk, O. |
| 2009 | Pharmacogenomics of Tamoxifen Therapy | Brauch, H.; Murdter, T.; Eichelbaum, M.; Schwab, M. |
| 2007 | Predictive value of known and novel alleles ofCYP2B6 for efavirenz plasma concentrations in HIV-infected individuals | Rotger, M.; Tegude, H.; Colombo, S.; Cavassini, M.; Furrer, H.; Decosterd, L.; Blievernicht, J.; Saussele, T.; Gunthard, H.; Schwab, M.; Eichelbaum, M.; Telenti, A.; Zanger, U. |
| 2008 | Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial | Morike, K.; Kivisto, K.; Schaeffeler, E.; Jagle, C.; Igel, S.; Drescher, S.; Fux, R.; Marx, C.; Hofmann, U.; Engel, C.; Wagner, F.; Delabar, U.; Meisner, C.; Bail, D.; Bohm, J.; Gleiter, C.; Ziemer, G.; Rein, J.; Hellberg, K.; Eichelbaum, M.; et al. |
| 2010 | Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding | Istrate, M.; Nussler, A.; Eichelbaum, M.; Burk, O. |
| 2008 | Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group | Schwab, M.; Zanger, U.; Marx, C.; Schaeffeler, E.; Klein, K.; Dippon, J.; Kerb, R.; Blievernicht, J.; Fischer, J.; Hofmann, U.; Bokemeyer, C.; Eichelbaum, M. |
| 2007 | Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole | Saussele, T.; Burk, O.; Blievernicht, J.; Nussler, A.; Nussler, N.; Hengstler, J.; Eichelbaum, M.; Schwab, M.; Zanger, U. |
| 2002 | Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters | Glaeser, H.; Drescher, S.; Van der Kuip, H.; Behrens, C.; Geick, A.; Burk, O.; Dent, J.; Somogyi, A.; von Richter, O.; Griese, E.; Eichelbaum, M.; Fromm, M. |
| 2003 | Stereochemical aspects of drug action and disposition | Eichelbaum, M.; Testa, B.; Somogyi, A. |
| 2003 | Stereoselective drug metabolism and drug interactions | Gross, A.; Somogyi, A.; Eichelbaum, M. |
| 2015 | Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer | Saladores, P.; Muerdter, T.; Eccles, D.; Chowbay, B.; Zgheib, N.; Winter, S.; Ganchev, B.; Eccles, B.; Gerty, S.; Tfayli, A.; Lim, J.; Yap, Y.; Ng, R.; Wong, N.; Dent, R.; Habbal, M.; Schaeffeler, E.; Eichelbaum, M.; Schroth, W.; Schwab, M.; et al. |
| 2008 | TGFβ2 and TβRII are valid molecular biomarkers for the antiproliferative effects of tamoxifen and tamoxifen metabolites in breast cancer cells | Buck, M.; Coller, J.; Murdter, T.; Eichelbaum, M.; Knabbe, C. |
