Showing results 17 to 33 of 33
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| Preview | Issue Date | Title | Author(s) |
| 2004 | Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity | Coller, J.; Krebsfaenger, N.; Klein, K.; Wolbold, R.; Nussler, A.; Neuhaus, P.; Zanger, U.; Eichelbaum, M.; Murdter, T. |
| 2007 | Molecular mechanism of basal CYP3A4 regulation by hepatocyte nuclear factor 4a: Evidence for direct regulation in the intestine | Tegude, H.; Schnabel, A.; Zanger, U.; Klein, K.; Eichelbaum, M.; Burk, O. |
| 2009 | Pharmacogenomics of Tamoxifen Therapy | Brauch, H.; Murdter, T.; Eichelbaum, M.; Schwab, M. |
| 2007 | Predictive value of known and novel alleles ofCYP2B6 for efavirenz plasma concentrations in HIV-infected individuals | Rotger, M.; Tegude, H.; Colombo, S.; Cavassini, M.; Furrer, H.; Decosterd, L.; Blievernicht, J.; Saussele, T.; Gunthard, H.; Schwab, M.; Eichelbaum, M.; Telenti, A.; Zanger, U. |
| 2008 | Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial | Morike, K.; Kivisto, K.; Schaeffeler, E.; Jagle, C.; Igel, S.; Drescher, S.; Fux, R.; Marx, C.; Hofmann, U.; Engel, C.; Wagner, F.; Delabar, U.; Meisner, C.; Bail, D.; Bohm, J.; Gleiter, C.; Ziemer, G.; Rein, J.; Hellberg, K.; Eichelbaum, M.; et al. |
| 2010 | Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding | Istrate, M.; Nussler, A.; Eichelbaum, M.; Burk, O. |
| 2008 | Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group | Schwab, M.; Zanger, U.; Marx, C.; Schaeffeler, E.; Klein, K.; Dippon, J.; Kerb, R.; Blievernicht, J.; Fischer, J.; Hofmann, U.; Bokemeyer, C.; Eichelbaum, M. |
| 2007 | Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole | Saussele, T.; Burk, O.; Blievernicht, J.; Nussler, A.; Nussler, N.; Hengstler, J.; Eichelbaum, M.; Schwab, M.; Zanger, U. |
| 2002 | Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters | Glaeser, H.; Drescher, S.; Van der Kuip, H.; Behrens, C.; Geick, A.; Burk, O.; Dent, J.; Somogyi, A.; von Richter, O.; Griese, E.; Eichelbaum, M.; Fromm, M. |
| 2003 | Stereochemical aspects of drug action and disposition | Eichelbaum, M.; Testa, B.; Somogyi, A. |
| 2003 | Stereoselective drug metabolism and drug interactions | Gross, A.; Somogyi, A.; Eichelbaum, M. |
| 2015 | Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer | Saladores, P.; Muerdter, T.; Eccles, D.; Chowbay, B.; Zgheib, N.; Winter, S.; Ganchev, B.; Eccles, B.; Gerty, S.; Tfayli, A.; Lim, J.; Yap, Y.; Ng, R.; Wong, N.; Dent, R.; Habbal, M.; Schaeffeler, E.; Eichelbaum, M.; Schroth, W.; Schwab, M.; et al. |
| 2008 | TGFβ2 and TβRII are valid molecular biomarkers for the antiproliferative effects of tamoxifen and tamoxifen metabolites in breast cancer cells | Buck, M.; Coller, J.; Murdter, T.; Eichelbaum, M.; Knabbe, C. |
| 2010 | The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P-glycoprotein) and consequences for the disposition of digoxin | Burk, O.; Brenner, S.; Hofmann, U.; Tegude, H.; Igel, S.; Schwab, M.; Eichelbaum, M.; Alscher, M. |
| 2002 | The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver | Coller, J.; Krebsfaenger, N.; Klein, K.; Endrizzi, K.; Wolbold, R.; Lang, T.; Nussler, A.; Neuhaus, P.; Zanger, U.; Eichelbaum, M.; Murdter, T. |
| 2009 | Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Münster protocols | Stanulla, M.; Schaeffeler, E.; Moricke, A.; Coulthard, S.; Cario, G.; Schrauder, A.; Kaatsch, P.; Dordelmann, M.; Welte, K.; Zimmerman, M.; Reiter, A.; Eichelbaum, M.; Riehm, H.; Schrappe, M.; Schwab, M. |
| 2008 | Variability in human hepatic MRP4 expression: Influence of cholestasis and genotype | Gradhand, U.; Lang, T.; Schaeffeler, E.; Glaeser, H.; Tegude, H.; Klein, K.; Fritz, P.; Jedlitschky, G.; Kroemer, H.; Bachmakov, I.; Anwald, B.; Kerb, R.; Zanger, U.; Eichelbaum, M.; Schwab, M.; Fromm, M. |
