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https://hdl.handle.net/2440/14270
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Type: | Journal article |
Title: | A review of biological indicators of illicit drug use, practical considerations and clinical usefulness. |
Author: | Wolff, K. Farrell, M. Marsden, J. Monteiro, M. Ali, R. Welch, S. Strang, J. |
Citation: | Addiction, 1999; 94(9):1279-1298 |
Publisher: | WILEY |
Issue Date: | 1999 |
ISSN: | 0965-2140 1360-0443 |
Statement of Responsibility: | K. Wolff, M. Farrell, J. Marsden, M. G. Monteiro, R. Ali, S. Welch, J. Strang |
Abstract: | <h4>Aims</h4>To examine a range of biological indicators of illicit drug use, including blood, urine, hair and saliva, addressing both technological and practical issues relating to their application and interpretation.<h4>Methods</h4>The review process involved an examination of key reference texts and literature from the scientific fields of analytical and clinical toxicology.<h4>Findings</h4>Urine remains the biological tool of choice for qualitative detection of illicit drug use in a clinical setting, while quantitative accuracy remains strictly the domain of blood. The growing sophistication of laboratory analysis may additionally make possible the routine use of hair sampling which can provide a much longer time frame for assessment. Breath, saliva, sweat or breast milk remain possibilities in the future.<h4>Conclusions</h4>Accurate interpretation of the screening tests within a clinical setting alongside other relevant information remains the key to the usefulness of any test. |
Keywords: | Humans Substance-Related Disorders Health Status Indicators Substance Abuse Detection Biomarkers |
DOI: | 10.1046/j.1360-0443.1999.94912792.x |
Published version: | http://dx.doi.org/10.1046/j.1360-0443.1999.94912792.x |
Appears in Collections: | Aurora harvest 7 Pharmacology publications |
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