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https://hdl.handle.net/2440/14309
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DC Field | Value | Language |
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dc.contributor.author | Lloyd, J. | - |
dc.contributor.author | Bochner, F. | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Australian Prescriber, 1996; 19(3):79-81 | - |
dc.identifier.issn | 0312-8008 | - |
dc.identifier.issn | 1839-3942 | - |
dc.identifier.uri | http://hdl.handle.net/2440/14309 | - |
dc.description.abstract | Aspirin reduces the risk of non-fatal stroke, non-fatal myocardial infarction and vascular death in patients at high risk of arterial thrombosis. Platelet function is inhibited by doses of 40-160 mg daily. In clinical trials performed before 1985, doses of 500-1500 mg daily were found to be effective. Since 1985, low doses have been evaluated and a meta-analysis has shown that daily doses of 75-150 mg are as effective as the previously used higher doses. The risk of adverse effects is dose-dependent above 75 mg daily. The maximum benefit:risk ratio is likely to be achieved with doses of 75-150 mg daily. In Australia, this is best achieved by either a single 100 mg tablet or half a 300 mg tablet taken daily. | - |
dc.description.statementofresponsibility | John Lloyd, Felix Bochner | - |
dc.language.iso | en | - |
dc.publisher | Australian Prescriber | - |
dc.source.uri | http://www.australianprescriber.com/magazine/19/3/79/81/ | - |
dc.subject | formulation | - |
dc.subject | clinical trials | - |
dc.subject | adverse effects | - |
dc.subject | platelet function | - |
dc.title | Aspirin: How low is low dose? | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.18773/austprescr.1996.070 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 2 Pharmacology publications |
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