Adelaide Research & Scholarship
Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/14640
| Citations | ||
| Scopus | Web of Science® | Altmetric |
|---|---|---|
|
?
|
?
|
|
| Type: | Journal article |
| Title: | Tumor necrosis factor primes neutrophils to kill Staphylococcus aureus by an oxygen-dependent mechanism and Plasmodium falciparum by an oxygen-independent mechanism |
| Author: | Kowanko, I. Ferrante, A. Clemente, G. Kumaratilake, L. |
| Citation: | Infection and Immunity, 1996; 64(8):3435-3437 |
| Publisher: | AMER SOC MICROBIOLOGY |
| Issue Date: | 1996 |
| ISSN: | 0019-9567 1098-5522 |
| Statement of Responsibility: | I. C. Kowanko, A. Ferrante, G. Clemente and L. M. Kumaratilake |
| Abstract: | The cytokine tumor necrosis factor (TNF) plays the important role of priming neutrophils for increased antimicrobial activity. We now demonstrate that human neutrophils which lack the ability to generate oxygen radicals, from patients with chronic granulomatous disease, show TNF-induced enhancement of killing of intraerythrocytic stages of Plasmodium falciparum but not of Staphylococcus aureus. |
| Keywords: | Erythrocytes Animals Humans Plasmodium falciparum Staphylococcus aureus Granulomatous Disease, Chronic Reactive Oxygen Species Tumor Necrosis Factor-alpha Free Radical Scavengers Neutrophil Activation |
| Rights: | Copyright © 1996, American Society for Microbiology |
| DOI: | 10.1128/iai.64.8.3435-3437.1996 |
| Published version: | http://iai.asm.org/cgi/content/abstract/64/8/3435 |
| Appears in Collections: | Aurora harvest 2 Nursing publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.