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https://hdl.handle.net/2440/16642
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dc.contributor.author | Pearson, S. | - |
dc.contributor.author | Maddern, G. | - |
dc.contributor.author | Fitridge, R. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | British Journal of Health Psychology, 2005; 10(2):299-310 | - |
dc.identifier.issn | 1359-107X | - |
dc.identifier.issn | 2044-8287 | - |
dc.identifier.uri | http://hdl.handle.net/2440/16642 | - |
dc.description | © 2005 The British Psychological Society | - |
dc.description.abstract | Objectives: The psychophysiological model of adjustment to surgery predicts associations between (1) heightened pre-operative state-anxiety and intra-operative neuroendocrine responses, (2) neuroendocrine responses and complications; and (3) heightened pre-operative state-anxiety and post-operative recovery. The present study examined these associations. Methods: Participants were 39 patients (mean age 71.9 ± 6.1 years) undergoing elective carotid endarterectomy surgery under local anaesthesia. In the week prior to surgery, patients completed baseline measures of physical and mental functioning using the MOS 36-item Short-Form Health Survey (SF-36). In addition to this, they undertook a 24-hour urine save to measure cortisol and catecholamines. Measures of state-anxiety were completed on the evening prior to surgery. A second 24-hour urine save was started at the time of anaesthetic induction. Follow-up measures of physical and mental functioning were completed 1 month following surgery. All complications were recorded during hospitalization. Results: There was a significant negative association between pre-operative state-anxiety and intra-operative cortisol (r = −.52, p ≤ .001). Using hierarchical regression analysis, pre-operative state-anxiety accounted for 10% of the variance in intra-operative cortisol responses after controlling for medical and demographic factors. There were no significant associations between neuroendocrine responses and complications. Pre-operative state-anxiety was a significant determinant of poorer mental functioning following surgery, explaining 10% of the variance in scores after adjusting for baseline mental functioning. Conclusions: Results from this study show increasing pre-operative anxiety to be associated with lower intra-operative cortisol responses and poorer mental functioning 1 month following surgery. | - |
dc.description.statementofresponsibility | Sue Pearson, Guy J. Maddern and Robert Fitridge | - |
dc.language.iso | en | - |
dc.publisher | British Psychological Soc | - |
dc.source.uri | http://dx.doi.org/10.1348/135910705x26957 | - |
dc.subject | Healing | - |
dc.subject | Adjustment (Psychology) | - |
dc.subject | Anxiety | - |
dc.subject | Patients | - |
dc.subject | Psychophysiology | - |
dc.title | The role of pre-operative state-anxiety in the determination of intra-operative neuroendocrine responses and recovery | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1348/135910705X26957 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Maddern, G. [0000-0003-2064-181X] | - |
dc.identifier.orcid | Fitridge, R. [0000-0001-6258-5997] | - |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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