Adelaide Research & Scholarship
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https://hdl.handle.net/2440/18949
| Type: | Thesis |
| Title: | Human GM-CSF, IL-3 and IL-5 receptor expression and their functional domains studied with monoclonal antibodies / Qiyu Sun. |
| Author: | Sun, Qiyu |
| Issue Date: | 1997 |
| School/Discipline: | Dept. of Medicine |
| Abstract: | This thesis developes specific tools to monitor receptor expression in a ligand-independent manner, demonstrates the receptor expression is not static and can be modulated by cytokines, identifies strong evidence in defining the N-terminal domain of IL-3R & chain and B'C' and F'G' loopes of domain 4 of Bc as functional domains involved in ligand binding and function and provides novel potential therapeutics. |
| Dissertation Note: | Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1997 |
| Subject: | Cytokines. Monoclonal antibodies. Ligand binding (Biochemistry) |
| Description: | Bibliography: leaves 123-141. xv, 141 leaves : ill. (some col.) ; 30 cm. |
| Provenance: | This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals |
| Appears in Collections: | Research Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01front.pdf | 407.99 kB | Adobe PDF | View/Open | |
| 02whole.pdf | 8.1 MB | Adobe PDF | View/Open |
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