Characterization of the CD44 v6 transcripts expressed in resting and activated human peripheral blood cells / by Peter Laslo.

Abstract

Examines the CD44 v6 transcripts in human peripheral blood mononuclear cells with specific aims to: define the CD44 v6 exon containing transcripts expressed in resting peripheral blood mononuclear cells; characterize expression of these transcripts following in vitro and in vivo cellular activation by respective analysis of mitogenically stimulated peripheral blood mononuclear cells and peripheral blood mononuclear cells isolated from renal transplant patients; and, individually clone the CD44 v6 full length cDNA transcripts and ascertain their functional role during T cell activation.