Mechanisms of intracellular and extracellular cytokine production from the human leukaemia inhibitory factor gene / Roger Bruce Voyle.

Abstract

The findings establish leukemia inhibitory factor, and possibly oncostatin M, as new members of a small but growing class of cytokines produced in an intracellularly active form and also suggest that the production of alternate transcripts and intercellularly-retained proteins may be a common and important feature of cytokines of the IL-6 and other families.