Adelaide Research & Scholarship
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https://hdl.handle.net/2440/21793
| Type: | Thesis |
| Title: | The Mammalian mitochondrial Hsp70 chaperone system, new GrpE-like members and novel organellar substrates / by Dean Jason Naylor. |
| Author: | Naylor, Dean Jason |
| Issue Date: | 1999 |
| School/Discipline: | Dept. of Horticulture, Viticulture and Oenology |
| Abstract: | The DnaK (Hsp70), DnaJ and GrpE heat shock proteins of Escherichia coli work synergistically in a diverse number of vital cellular processes including the folding of nascent polypeptides, assembly and disassembly of multimeric proteins, refolding of malfolded proteins, degredation of unstable and non-native polypeptides, regulation of the stress response and the mediation of protein translocation across membranes. In this study Dna-K-affinity purification was employed to identify a mammalian mitrochondrial GrpE homologue (mt-GrpE#1) for the first time. The results are discussed. |
| Dissertation Note: | Thesis (Ph.D.)--University of Adelaide, Dept. of Horticulture, Viticulture and Oenology |
| Description: | Bibliography: leaves 104-136. xii, 136 leaves : ill. (some col.), tables ; 30 cm. |
| Provenance: | This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals |
| Appears in Collections: | Research Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01front.pdf | 189.36 kB | Adobe PDF | View/Open | |
| 02whole.pdf | 12.97 MB | Adobe PDF | View/Open |
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