Adelaide Research & Scholarship
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https://hdl.handle.net/2440/22100
| Type: | Thesis |
| Title: | Chemotherapy-induced mucositis : mechanisms of damage, time course of events and possible preventative strategies / Rachel J. Gibson. |
| Author: | Gibson, Rachel J. (Rachel Jane) |
| Issue Date: | 2004 |
| School/Discipline: | Dept. of Medicine |
| Abstract: | Attempts to build a complete understanding of the cellular mechanisms associated with gastrointestinal mucositis through investigations of the effects throughout the gastrointestinal tract of chemotherapeutic agents Methotrexate and Irinotecan, the possible ameliorating potential of the cytokine Interleukin-11 in reducing the side effects of chemotherapy, the expression of pro- and anti-apoptopic proteins and transcription factors along the gastrointestinal tract in normal human patients and the time-course of development of oral mucositis in human patients. Suggests that the entire gastrointestinal tract follows a similar pattern of development of mucositis. |
| Dissertation Note: | Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2004 |
| Subject: | Gastrointestinal mucosa Diseases. Oral mucosa Diseases. Cancer Chemotherapy Complications. |
| Description: | "April 2004" Bibliography: leaves 121-142. xviii, 142, [19] leaves : ill. (some col.), plates (some col.) ; 30 cm. |
| Provenance: | This electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exception. If you are the author of this thesis and do not wish it to be made publicly available or If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legals. Copyright material removed from digital thesis. See print copy in University of Adelaide Library for full text. |
| Appears in Collections: | Research Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01front.pdf | 198.76 kB | Adobe PDF | View/Open | |
| 02whole.pdf | 7.91 MB | Adobe PDF | View/Open | |
| Permissions Restricted Access | Library staff access only | 262.41 kB | Adobe PDF | View/Open |
| Restricted Restricted Access | Library staff access only | 10.47 MB | Adobe PDF | View/Open |
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