Regulation of expression and activity of the late gene activator, B, of bacteriophage 186 / Rachel Ann Schubert.

Abstract

"The aims of this thesis were to investigate potentially novel aspects of the regulation of B and morphogenetic gene expression in coliphage 186, in order to understand more fully how late gene expression is controlled in this phage, and how gene expression may be regulated in general. Three specific aims were pursued in this project: 1. to characterize E. coli mutants that appear to abolish 186 B protein activity; 2. to determine the role of replication for the provision of late functions during the phage lytic cycle; and 3. to determine the role of CI repression of the 186 B promoter." --p. 41.