Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/28023
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Genes for cognitive function: Developments on the X |
Author: | Gecz, J. Mulley, J. |
Citation: | Genome Research, 2000; 10(2):157-163 |
Publisher: | Cold Spring Harbor Lab Press |
Issue Date: | 2000 |
ISSN: | 1088-9051 1549-5469 |
Abstract: | Developments in human genome research enabled the first steps toward a molecular understanding of cognitive function. That there are numerous genes on the X chromosome affecting intelligence at the lower end of the cognitive range is no longer in doubt. Naturally occurring mutations have so far led to the identification of seven genes accounting for a small proportion of familial nonspecific X-linked mental retardation. These new data indicate that normal expression of many more X-linked and autosomal genes contribute to cognitive function. The emerging knowledge implicating genes in intracellular signaling pathways provides the insight to identify as candidates other X-linked and autosomal genes regulating the normal development of cognitive function. Recent advances in unravelling the underlying molecular complexity have been spectacular but represent only the beginning, and new technologies will need to be introduced to complete the picture. |
Keywords: | X Chromosome Animals Humans Cognition Disorders Genetic Linkage |
DOI: | 10.1101/gr.10.2.157 |
Published version: | http://dx.doi.org/10.1101/gr.10.2.157 |
Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_28023.pdf | 1.29 MB | Publisher's PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.