Adelaide Research & Scholarship
Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/28204
| Citations | ||
| Scopus | Web of Science® | Altmetric |
|---|---|---|
|
?
|
?
|
|
| Type: | Journal article |
| Title: | The interaction of insulin-like growth factors (IGFs) with insulin-like growth factor binding proteins (IGFBPs): a review |
| Author: | Carrick, F. Wallace, J. Forbes, B. |
| Citation: | International Journal of Peptide Research and Therapeutics, 2002; 8(3-5):147-153 |
| Publisher: | Kluwer Academic Publ |
| Issue Date: | 2002 |
| ISSN: | 0929-5666 1573-3904 |
| Statement of Responsibility: | Francine E. Carrick, John C. Wallace and Briony E. Forbes |
| Abstract: | The interactions between insulin-like growth factor bindingproteins (IGFBPs) and insulin-like growth factors (IGFs)are important in regulating the availability of IGFs to thetype 1 IGF receptor (IGF1R) but there is still a lack ofinformation regarding the mechanism of IGF binding byIGFBPs. While many studies have defined general regions ofthe IGFBPs that interact with IGFs, only recently havespecific IGF binding residues been described. This reviewwill outline the structural evidence describing residues ofboth the IGFBPs and IGFs involved in the IGFBP-IGFinteraction. |
| Keywords: | binding site IGF IGFBP IGFBP-IGF complex structure |
| Description: | The original publication is available at www.springerlink.com |
| DOI: | 10.1023/A:1016253819108 |
| Published version: | http://dx.doi.org/10.1007/bf02446511 |
| Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.