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Results 31-39 of 39 (Search time: 0.003 seconds).
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Issue Date
Title
Author(s)
2010
Phase III, randomized, open-label study of daily Imatinib Mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: Tyrosine Kinase Inhibitor Optimization and Selectivity Study
Cortes, A.
;
Baccarani, M.
;
Guilhot, F.
;
Druker, B.
;
Branford, S.
;
Kim, D.
;
Pane, F.
;
Pasquini, R.
;
Goldberg, S.
;
Kalaycio, M.
;
Moiraghi, B.
;
Rowe, J.
;
Tothova, E.
;
de Souza, C.
;
Rudoltz, M.
;
Yu, R.
;
Krahnke, T.
;
Kantarjian, H.
;
Radich, J.
;
Hughes, T.
2010
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with Imatinib
White, D.
;
Dang, P.
;
Engler, J.
;
Frede, A.
;
Osborn, M.
;
Saunders, V.
;
Manley, P.
;
Zrim, S.
;
Hughes, T.
2011
BCR-ABL transcript dynamics support the hypothesis that leukemic stem cells are reduced during imatinib teatment
Stein, A.
;
Bottino, D.
;
Modur, V.
;
Branford, S.
;
Kaeda, J.
;
Goldman, J.
;
Hughes, T.
;
Radich, J.
;
Hochhaus, A.
2011
SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia
Esposito, N.
;
Colavita, I.
;
Quintarelli, C.
;
Sica, A.
;
Peluso, A.
;
Luciano, L.
;
Picardi, M.
;
Vecchio, L.
;
Buonomo, T.
;
Hughes, T.
;
White, D.
;
Radich, J.
;
Russo, D.
;
Branford, S.
;
Saglio, G.
;
Vaz de Melo, J.
;
Martinelli, R.
;
Ruoppolo, M.
;
Kalebic, T.
;
Martinelli, G.
;
et al.
2008
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications
Hiwase, D.
;
Saunders, V.
;
Hewett, D.
;
Frede, A.
;
Zrim, S.
;
Dang, P.
;
Eadie, L.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
;
White, D.
2012
Therapeutic targeting of BCR-ABL: prognostic markers of response and resistance mechanism in chronic myeloid leukaemia
Yeung, D.
;
Hughes, T.
2013
Dasatinib targets chronic myeloid leukemia-CD34⁺ progenitors as effectively as it targets mature cells
Hiwase, D.
;
Saunders, V.
;
Nievergall, E.
;
Ross, D.
;
White, D.
;
Hughes, T.
2017
Increased peroxisome proliferator-activated receptor γ activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells
Wang, J.
;
Lu, L.
;
Kok, C.
;
Saunders, V.
;
Goyne, J.
;
Dang, P.
;
Leclercq, T.
;
Hughes, T.
;
White, D.
2017
CML patients with deep molecular responses to TKI have restored immune effectors and decreased PD-1 and immune suppressors
Hughes, A.
;
Clarson, J.
;
Tang, C.
;
Vidovic, L.
;
White, D.
;
Hughes, T.
;
Yong, A.
Discover
Author
16
Hochhaus, A.
14
White, D.
12
Radich, J.
12
Saglio, G.
11
Branford, S.
10
Kantarjian, H.
10
Larson, R.
8
Baccarani, M.
8
Guilhot, F.
8
Kim, D.
.
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Subject
35
Pyrimidines
34
Imatinib Mesylate
32
Benzamides
32
Piperazines
28
Leukemia, Myelogenous, Chronic, B...
19
Fusion Proteins, bcr-abl
19
Protein Kinase Inhibitors
16
Male
15
Female
15
Middle Aged
.
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Date issued
25
2010 - 2017
14
2002 - 2009