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Results 51-60 of 60 (Search time: 0.003 seconds).
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Issue Date
Title
Author(s)
2003
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
Branford, S.
;
Rudzki, Z.
;
Walsh, S.
;
Parkinson, I.
;
Grigg, A.
;
Szer, J.
;
Taylor, K.
;
Hermann, R.
;
Seymour, J.
;
Arthur, C.
;
Joske, D.
;
Lynch, K.
;
Hughes, T.
2011
BCR-ABL transcript dynamics support the hypothesis that leukemic stem cells are reduced during imatinib teatment
Stein, A.
;
Bottino, D.
;
Modur, V.
;
Branford, S.
;
Kaeda, J.
;
Goldman, J.
;
Hughes, T.
;
Radich, J.
;
Hochhaus, A.
2011
SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia
Esposito, N.
;
Colavita, I.
;
Quintarelli, C.
;
Sica, A.
;
Peluso, A.
;
Luciano, L.
;
Picardi, M.
;
Vecchio, L.
;
Buonomo, T.
;
Hughes, T.
;
White, D.
;
Radich, J.
;
Russo, D.
;
Branford, S.
;
Saglio, G.
;
Vaz de Melo, J.
;
Martinelli, R.
;
Ruoppolo, M.
;
Kalebic, T.
;
Martinelli, G.
;
et al.
2008
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications
Hiwase, D.
;
Saunders, V.
;
Hewett, D.
;
Frede, A.
;
Zrim, S.
;
Dang, P.
;
Eadie, L.
;
To, L.
;
Vaz de Melo, J.
;
Kumar, S.
;
Hughes, T.
;
White, D.
2012
Therapeutic targeting of BCR-ABL: prognostic markers of response and resistance mechanism in chronic myeloid leukaemia
Yeung, D.
;
Hughes, T.
2013
Clarithromycin enhances dasatinib-induced cell death in chronic myeloid leukemia cells, by inhibition of late stage autophagy
Schafranek, L.
;
Leclercq, T.
;
White, D.
;
Hughes, T.
2013
Dasatinib targets chronic myeloid leukemia-CD34⁺ progenitors as effectively as it targets mature cells
Hiwase, D.
;
Saunders, V.
;
Nievergall, E.
;
Ross, D.
;
White, D.
;
Hughes, T.
2005
Inhibition of c-fms by imatinib - Expanding the spectrum of treatment
Dewar, A.
;
Zannettino, A.
;
Hughes, T.
;
Lyons, A.
2017
Increased peroxisome proliferator-activated receptor γ activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells
Wang, J.
;
Lu, L.
;
Kok, C.
;
Saunders, V.
;
Goyne, J.
;
Dang, P.
;
Leclercq, T.
;
Hughes, T.
;
White, D.
2017
CML patients with deep molecular responses to TKI have restored immune effectors and decreased PD-1 and immune suppressors
Hughes, A.
;
Clarson, J.
;
Tang, C.
;
Vidovic, L.
;
White, D.
;
Hughes, T.
;
Yong, A.
Discover
Author
23
White, D.
21
Branford, S.
16
Hochhaus, A.
10
Radich, J.
9
Cortes, J.
9
Saunders, V.
7
Kantarjian, H.
7
Saglio, G.
7
Yeung, D.
7
Zannettino, A.
.
next >
Subject
43
Pyrimidines
38
Imatinib Mesylate
36
Benzamides
36
Piperazines
28
Antineoplastic Agents
27
Fusion Proteins, bcr-abl
27
Protein Kinase Inhibitors
19
Male
18
Treatment Outcome
17
Adult
.
next >
Date issued
1
2020 - 2022
32
2010 - 2019
27
2000 - 2009