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https://hdl.handle.net/2440/3041
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Type: | Journal article |
Title: | Distribution of the saa gene in strains of Shiga toxin-producing Escherichia coli of human and bovine origins |
Author: | Jenkins, C. Perry, N. Cheasty, T. Shaw, D. Frankel, G. Dougan, G. Gunn, G. Smith, H. Paton, A. Paton, J. |
Citation: | Journal of Clinical Microbiology, 2003; 41(4):1775-1778 |
Publisher: | Amer Soc Microbiology |
Issue Date: | 2003 |
ISSN: | 0095-1137 1098-660X |
Statement of Responsibility: | Claire Jenkins, Neil T. Perry, Tom Cheasty, Darren J. Shaw, Gad Frankel, Gordon Dougan, George J. Gunn, Henry R. Smith, Adrienne W. Paton, and James C. Paton |
Abstract: | Certain strains of Shiga toxin-producing Escherichia coli (STEC) which do not have the locus of enterocyte effacement pathogenicity island carry the STEC autoagglutinating adhesin (saa) gene. The distribution of the saa gene in STEC isolates from patients with hemolytic-uremic syndrome (HUS), patients with less severe diarrheal disease, asymptomatic individuals, and healthy cattle was examined. saa-positive strains were detected more frequently (P < 0.001) in STEC strains from bovines (32 of 56 strains) than in those from humans (8 of 91 strains). No significant association (P = 0.135) was found between the saa gene and STEC isolated from patients with HUS (6 of 46 strains) or diarrhea (2 of 29 strains) and from healthy controls (0 of 16 strains). |
Keywords: | Feces Animals Cattle Humans Escherichia coli Escherichia coli Infections Hemolytic-Uremic Syndrome Diarrhea Adhesins, Bacterial Escherichia coli Proteins Shiga Toxins |
DOI: | 10.1128/JCM.41.4.1775-1778.2003 |
Published version: | http://jcm.asm.org/cgi/content/abstract/41/4/1775 |
Appears in Collections: | Aurora harvest 2 Molecular and Biomedical Science publications |
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