Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/3092
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Factors associated with maintenance of wakefulness test mean sleep latency in patients with mild to moderate obstructive sleep apnoea and normal subjects |
Author: | Banks, S. Barnes, M. Tarquinio, N. Pierce, R. Lack, L. McEvoy, R. |
Citation: | Journal of Sleep Research, 2004; 13(1):71-78 |
Publisher: | Blackwell Publishing Ltd |
Issue Date: | 2004 |
ISSN: | 0962-1105 1365-2869 |
Statement of Responsibility: | Banks, Siobhan; Barnes, Maree; Tarquinio, Natalie Pierce, Robert J.; Lack, Leon C.; Doug Mcevoy, R. |
Abstract: | This study investigated the possible factors related to the Maintenance of Wakefulness Test (MWT) mean sleep latency. A second analysis explored the characteristics of subjects who had discrepant Epworth Sleepiness Scale (ESS) and MWT scores. A total of 151 subjects (110 mild to moderate obstructive sleep apnoea (OSA) patients and 41 control subjects) were recruited for the study. The subjects completed an overnight Polysomnography (PSG), MWT, cognitive, performance and vigilance tasks and answered self-report questionnaires on mood and sleepiness. A forward stepwise multiple regression was performed on MWT mean sleep latency. The predictor variables age (r = 0.28), subjective sleep history for 1 week prior to MWT (sleep diary; r = 0.19) and number of >4% SaO2 Dips during the PSG (r = -0.21) best explained the MWT results, but only accounted for 12.8% of the variance in the test. It was found that 33% of subjects had discrepant ESS and MWT scores. A new variable was created to analyse these subjects (MWT/ESS discrepancy score; MED). A forward stepwise multiple regression analysis found that depression, performance errors and sleep disordered breathing explained 13.4% of the variance in MED scores. The MWT is a complex behavioural test whose scores do not seem to have a very robust relationship with potential predictors and co-correlates. Further comprehensive study is needed if the test is to be used in a diagnostically meaningful way. |
Keywords: | Humans Sleep Apnea, Obstructive Disorders of Excessive Somnolence Electrocardiography Electroencephalography Electrooculography Polysomnography Body Mass Index Severity of Illness Index Factor Analysis, Statistical Wakefulness Sleep Time Factors |
DOI: | 10.1111/j.1365-2869.2003.00383.x |
Published version: | http://dx.doi.org/10.1111/j.1365-2869.2003.00383.x |
Appears in Collections: | Aurora harvest 6 Molecular and Biomedical Science publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.