Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/32702
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Type: | Journal article |
Title: | Visual field loss associated with vigabatrin: pathological correlations |
Author: | Ravindran, J. Blumbergs, P. Crompton, J. Pietris, G. Waddy, H. |
Citation: | Journal of Neurology, Neurosurgery and Psychiatry, 2001; 70(6):787-789 |
Publisher: | British Med Journal Publ Group |
Issue Date: | 2001 |
ISSN: | 0022-3050 1468-330X |
Abstract: | Pathological changes are reported in the anterior visual pathways of a 41 year old man with complex partial seizures treated with vigabatrin who developed bilateral visual field constriction. There was peripheral retinal atrophy with loss of ganglion cells and loss of nerve fibres in the optic nerves, chiasm, and tracts. No evidence of intramyelinic oedema was seen. These findings suggest that the primary site of injury lies within the ganglion cells in the retina. The degree of atrophy seen would suggest that the visual field loss is irreversible. |
Keywords: | Visual Pathways Retina Humans Epilepsy, Complex Partial Vigabatrin Anticonvulsants Visual Fields Adult Male |
Description: | © 2001 by Journal of Neurology, Neurosurgery, and Psychiatry |
DOI: | 10.1136/jnnp.70.6.787 |
Published version: | http://jnnp.bmj.com/cgi/content/abstract/70/6/787 |
Appears in Collections: | Aurora harvest Pathology publications |
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hdl_32702.pdf | 149.04 kB | Publisher's PDF | View/Open |
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