Adelaide Research & Scholarship
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https://hdl.handle.net/2440/34454
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| Type: | Journal article |
| Title: | Total synthesis of variolin B |
| Author: | Anderson, Regan James Morris, Jonathan Charles |
| Citation: | Tetrahedron Letters, 2001; 42(49):8697-8699 |
| Publisher: | Pergamon / Elsevier |
| Issue Date: | 2001 |
| ISSN: | 0040-4039 |
| School/Discipline: | School of Chemistry and Physics : Chemistry |
| Statement of Responsibility: | Regan J. Anderson and Jonathan C. Morris |
| Abstract: | The total synthesis of the marine alkaloid variolin B has been achieved in eight steps, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involves the tandem deoxygenation and cyclization of a triarylmethanol using a combination of triethylsilane and trifluoroacetic acid. |
| DOI: | 10.1016/S0040-4039(01)01881-0 |
| Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/233/description#description |
| Appears in Collections: | Chemistry and Physics publications |
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