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https://hdl.handle.net/2440/34890
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Type: | Journal article |
Title: | Ring-deactivated hydroxymethylpyrroles as inhibitors of α-chymotrypsin |
Other Titles: | Ring-deactivated hydroxymethylpyrroles as inhibitors of alpha-chymotrypsin |
Author: | Abell, A. Nabbs, B. |
Citation: | Bioorganic and Medicinal Chemistry, 2001; 9(3):621-628 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2001 |
ISSN: | 0968-0896 1464-3391 |
Statement of Responsibility: | Andrew D. Abell, and Brent K. Nabbs |
Abstract: | N-Acyl and N-sulfonylhydroxymetyhylpyrroles have been synthesised and shown to inhibit α-chymotrypsin. A hydrophobic group in the N-substituent has been shown to be required for activity. |
Keywords: | Animals Cattle Pyrroles Chymotrypsin Serine Proteinase Inhibitors Structure-Activity Relationship Kinetics |
Rights: | Copyright © 2001 Elsevier Science Ltd. All rights reserved. |
DOI: | 10.1016/S0968-0896(00)00274-1 |
Description (link): | http://www.sciencedirect.com/science/journal/09680896 |
Published version: | http://dx.doi.org/10.1016/s0968-0896(00)00274-1 |
Appears in Collections: | Aurora harvest Chemistry publications |
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