Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/36407
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Type: | Journal article |
Title: | Terahertz time-domain spectroscopy and imaging of artificial RNA |
Author: | Fischer, B. Hoffmann, M. Helm, H. Wilk, R. Rutz, F. Kleine-Ostmann, T. Koch, M. Jepsen, P. |
Citation: | Optics Express, 2005; 13(14):5205-5215 |
Publisher: | Optical Soc Amer |
Issue Date: | 2005 |
ISSN: | 1094-4087 1094-4087 |
Statement of Responsibility: | Bernd Fischer, Matthias Hoffmann, Hanspeter Helm, Rafal Wilk, Frank Rutz, Thomas Kleine-Ostmann, Martin Koch, Peter Jepsen |
Abstract: | We use terahertz time-domain spectroscopy (THz-TDS) to measure the far-infrared dielectric function of two artificial RNA single strands, composed of polyadenylic acid (poly-A) and polycytidylic acid (poly-C). We find a significant difference in the absorption between the two types of RNA strands, and we show that we can use this difference to record images of spot arrays of the RNA strands. Under controlled conditions it is possible to use the THz image to distinguish between the two RNA strands. We discuss the requirements to sample preparation imposed by the lack of sharp spectral features in the absorption spectra. |
Keywords: | Medical optics and biotechnology Medical and biological imaging Spectroscopy far infrared |
Description: | This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsexpress.org/abstract.cfm?id=84667. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law. |
Rights: | © 2005 Optical Society of America |
DOI: | 10.1364/OPEX.13.005205 |
Published version: | http://dx.doi.org/10.1364/opex.13.005205 |
Appears in Collections: | Aurora harvest Electrical and Electronic Engineering publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_36407.pdf | Published version | 400.66 kB | Adobe PDF | View/Open |
vers_hdl_36407.pdf | Version information | 73.64 kB | Adobe PDF | View/Open |
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