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https://hdl.handle.net/2440/39385
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DC Field | Value | Language |
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dc.contributor.author | Luke, C. | - |
dc.contributor.author | Coventry, B. | - |
dc.contributor.author | Foster-Smith, E. | - |
dc.contributor.author | Roder, D. | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Asian Pacific Journal of Cancer Prevention (APJCP), 2003; 4(4):307-311 | - |
dc.identifier.issn | 1513-7368 | - |
dc.identifier.issn | 2476-762X | - |
dc.identifier.uri | http://hdl.handle.net/2440/39385 | - |
dc.description.abstract | Secular trends in Clark level were investigated by Breslow category for 8,432 invasive cutaneous melanomas diagnosed in South Australia in 1980-2000. More recently diagnosed lesions were found to have deeper levels. After adjusting for age at diagnosis, tumour site, histology, and thickness measured in half millimetres, the relative odds (95% confidence limits) of penetration to the reticular dermis or subcutaneous fat were 1.99 (1.59, 2.50) for the 1987- 93 diagnostic period, and 2.82 (2.25, 3.54) for 1994-2000, when compared with 1980-86. After adjusting for melanoma thickness, the secular trends for deeper lesions applied to a broad cross-section of socio-demographic sub-groups, tumour sites, and histological types. While this similarity in trend would be consistent with a measurement effect, a real change cannot be ruled out and increased emphasis on earlier detection may be warranted. The prognostic implications of changes in inter-relationships between measures of thickness and level require periodic re-evaluation. | - |
dc.description.statementofresponsibility | Colin G. Luke, Brendon J. Coventry, Erwin J. Foster-Smith, David M. Roder | - |
dc.language.iso | en | - |
dc.publisher | Asian Pacific Organization for Cancer Prevention | - |
dc.rights | © Asian Pacific Organization for Cancer Prevention | - |
dc.source.uri | http://www.apocp.org/cancer_download/Vol4_No4/Colin%20Luke.pdf | - |
dc.subject | Cutaneous melanomas | - |
dc.subject | Clark level of invesion | - |
dc.subject | Breslow thickness | - |
dc.subject | Measurement effect | - |
dc.title | Are cutaneous melanomas of specified thickness showing deeper levels of invasion at diagnosis? | - |
dc.type | Journal article | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Coventry, B. [0000-0002-3596-7735] | - |
dc.identifier.orcid | Roder, D. [0000-0001-6442-4409] | - |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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