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https://hdl.handle.net/2440/39613
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Type: | Journal article |
Title: | Open mesh versus non-mesh repair of groin hernia meta-analysis of randomized trials leased on individual patient data |
Author: | Fingerhut, A. Go, P. Grant, A. Kingsnorth, A. Merello, J. O'Dwyer, P. Payne, J. McCormack, K. Ross, S. Scott, N. Vale, L. Aitola, P. Anderberg, B. Arvidsson, D. Barkun, J. Barth Jnr, R. Bay-Nielsen, M. Beets, G. Bittner, R. Bringman, S. et al. |
Citation: | Hernia, 2002; 6(3):130-136 |
Publisher: | Springer France |
Issue Date: | 2002 |
ISSN: | 1265-4906 1248-9204 |
Organisation: | The EU Hernia Trialists Collaboration |
Statement of Responsibility: | A.M. Grant (Guy John Maddern one of several collaborators) |
Abstract: | Background: The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries. Materials and methods: Twenty eligible trials (5016 participants) of open mesh vs. non-mesh groin hernia repair were identified. Meta-analysis was performed using raw individual patient data where possible. Results: Fewer hernia recurrences were reported after mesh repair. There were no clear differences between mesh and non-mesh groups in complications. Overall, those in the mesh groups had a shorter hospital stay, quicker return to usual activities and less frequent persisting pain, but individual trial results varied. Conclusions: The review provides strong evidence that open mesh repair is associated with a reduction in the risk of recurrence of between 50% and 75%. There is also some evidence of quicker recovery and of lower rates of persisting pain following open mesh repair. |
Keywords: | Inguinal hernia Individual patient data meta-analysis Randomised controlled trial Synthetic mesh Systematic review |
DOI: | 10.1007/s10029-002-0073-1 |
Published version: | http://dx.doi.org/10.1007/s10029-002-0073-1 |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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