The use of topical ozone to treat recurrent aphthous ulceration

Abstract

Recurrent aphthous ulceration is a common mucosal disorder that can be painful and debilitating for patients. This type of ulceration has been associated with systemic disease and it has been suggested that a variety of immunological, microbial and genetic factors may all play a role in its aetiopathogenesis. A wide variety of treatment strategies for aphthous ulceration has been discussed in the literature. This case report demonstrates the beneficial use of topical application of ozone using the Healozone‘ appliance (Kavo) in a patient with long standing aphthous ulceration involving the lateral border of the tongue. The topical application of ozone provided an effective means of producing resolution of clinical symptoms related to aphthous ulceration for this patient. Further clinical investigation is required in order to determine the potential of this treatment modality in the treatment of recurrent aphthous ulceration.