Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/40423
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Type: Journal article
Title: Domiciliary oxygen for interstitial lung disease
Author: Crockett, A.
Cranston, J.
Antic, N.
Citation: Cochrane Database of Systematic Reviews, 2001; 2001(3):Art no. CD002883-
Publisher: Update Software Ltd
Issue Date: 2001
ISSN: 1469-493X
1464-780X
Statement of
Responsibility: 
AJ Crockett, JM Cranston and N Antic
Abstract: <h4>Background</h4>Retrospective survival data have suggested poor effectiveness of oxygen therapy in patients with interstitial lung disease (ILD).<h4>Objectives</h4>To determine the effect of domiciliary oxygen therapy on survival and quality of life in patients with a diagnosis of ILD and hypoxaemia.<h4>Search strategy</h4>Randomized Controlled Trials (RCTs) were identified using the Cochrane Airways Group register and the search terms: (home OR domiciliary AND oxygen AND (Interstitial lung disease OR ILD OR pulmonary fibrosis OR IPF)).<h4>Selection criteria</h4>Any randomized controlled trial (RCT) in adult patients with hypoxaemia and ILD that compared long term domiciliary or home oxygen therapy with a control group.<h4>Data collection and analysis</h4>Only one unpublished RCT was identified.<h4>Main results</h4>Only one trial was identified. Mortality for both the oxygen treated and control groups was approximately 91% after 3 years (Peto odds ratio 0.99, 95% confidence intervals 0.16,6.26). The effect of oxygen therapy on quality of life and physiological parameters was not reported.<h4>Reviewer's conclusions</h4>The assumption that home oxygen therapy has a beneficial survival effect in patients with ILD has not been demonstrated in the single RCT identified.
Keywords: Humans
Lung Diseases, Interstitial
Oxygen Inhalation Therapy
Confidence Intervals
Odds Ratio
Quality of Life
Home Care Services
Randomized Controlled Trials as Topic
Description: Copyright © 2008 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.
DOI: 10.1002/14651858.CD002883
Published version: http://dx.doi.org/10.1002/14651858.cd002883
Appears in Collections:Aurora harvest 6
General Practice publications

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