Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/41428
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Reardon, K. | en |
dc.contributor.author | Heath, D. | en |
dc.contributor.author | Nimmo, A. | en |
dc.contributor.author | Vink, R. | en |
dc.contributor.author | Whitfield, K. | en |
dc.date.issued | 2004 | en |
dc.identifier.citation | 7th International Neurotrauma Symposium, Adelaide, Australia, 12-16 September, 2004: pp.115-118 | en |
dc.identifier.isbn | 88-7587-082-9 | en |
dc.identifier.isbn | 9788875870829 | en |
dc.identifier.uri | http://hdl.handle.net/2440/41428 | - |
dc.description | © 2004 by MEDIMOND The document attached has been archived with permission from the Medimond International Proceedings Division. An external link to the publisher’s web site is included. | en |
dc.description.abstract | A profound inflammatory response is initiated following traumatic brain injury (TBI). It has been proposed that serum IL-6 levels may serve as a marker for the severity of the injury. Using the rat impact-acceleration model of TBI, the study examined whether drugs which are able to inhibit neurogenic inflammation (capsaicin, NK1 antagonist), might influence the post-traumatic inflammatory response. In non-treated animals, TBI resulted in a significant increase in serum IL-6 levels. However, in animals pre-treated with capsaicin prior to injury, or treated with an NK1 antagonist following injury, this rise in IL-6 levels was not observed. We conclude that the inhibition of neurogenic inflammation may attenuate the inflammatory reaction associated with TBI, and help improve outcome. | en |
dc.description.statementofresponsibility | K. Reardon, D. Heath, A. Nimmo, R. Vink and K. Whitfield | en |
dc.description.uri | http://www.medimond.com/proceedings/moreinfo/20040912.htm | en |
dc.language.iso | en | en |
dc.publisher | Medimond International Proceedings | en |
dc.title | Inhibition of neurogenic inflammation attenuates the inflammatory response following traumatic brain injury in rats | en |
dc.type | Conference paper | en |
dc.contributor.conference | International Neurotrauma Symposium (7th : 2004 : Adelaide, S. Aust.) | en |
dc.publisher.place | Bologna, Italy | en |
pubs.publication-status | Published | en |
dc.identifier.orcid | Vink, R. [0000-0002-4885-0667] | en |
Appears in Collections: | Aurora harvest 6 Pathology publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_41428.pdf | 46.14 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.