Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/41430
Type: | Conference paper |
Title: | New developments in the pharmacologic management of posttraumatic oedema |
Author: | Vink, R. |
Citation: | 7th International Neurotrauma Symposium, Adelaide, Australia, 12-16 September, 2004: pp.55-60 |
Publisher: | Medimond International Proceedings |
Publisher Place: | Bologna, Italy |
Issue Date: | 2004 |
ISBN: | 88-7587-082-9 9788875870829 |
Conference Name: | International Neurotrauma Symposium (7th : 2004 : Adelaide, S. Aust.) |
Statement of Responsibility: | R. Vink |
Abstract: | A major risk factor contributing to increased mortality and morbidity following traumatic brain injury (TBI) is oedema formation. Recent efforts by our laboratory, and others, have concentrated on establishing the mechanisms associated with oedema formation following brain injury, and developing appropriate pharmacologic interventional therapies. Our own studies to date have shown that neurogenic inflammation is a major contributor to brain oedema formation. Attenuation of the neurogenic inflammation, either by preventing release of the neuropeptides or blocking substance P receptor binding, profoundly inhibited these events. We propose that pharmacologic intervention targeting neurogenic inflammation may be a promising strategy for the management of posttraumatic oedema. |
Description: | © 2004 by MEDIMOND The document attached has been archived with permission from the Medimond International Proceedings Division. An external link to the publisher’s web site is included. |
Description (link): | http://www.medimond.com/proceedings/moreinfo/20040912.htm |
Appears in Collections: | Aurora harvest Pathology publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
hdl_41430.pdf | 67.42 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.