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https://hdl.handle.net/2440/42068
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Type: | Journal article |
Title: | Atypical presentations of screen-detected DCIS Implications for pre-operative assessment and surgical intervention |
Author: | Farshid, G. Downey, P. Gill, P. |
Citation: | The Breast, 2007; 16(2):161-171 |
Publisher: | Churchill Livingstone |
Issue Date: | 2007 |
ISSN: | 0960-9776 1532-3080 |
Statement of Responsibility: | Gelareh Farshid, Peter Downey and P.Grantley Gill |
Abstract: | Few series are published on DCIS that forms parenchymal lesions on screening mammograms. The implications of these unusual presentations for pre-operative assessment and surgical intervention are of interest. In the setting of a large, population-based breast cancer screening program, the diagnostic and management implications of DCIS presenting as parenchymal lesions on screening mammograms are investigated. A total of 125 lesions (20.1% of all DCIS) presented as a mass (n=99) or microcalcifications with an associated parenchymal lesion (n=26). Cytology was positive in 47.1% of cases. Core biopsy diagnosed DCIS in 68.4% of cases. Breast surgery after a definite preoperative diagnosis achieved negative initial margins in 69.4% case, versus 54.7% without a pre-operative malignant diagnosis. The mastectomy rate was 26.4%. Axillary surgery was carried out in 32.8% cases, including axillary clearance in 26.4% of cases. One in five cases of DCIS detected during mammographic screening has features other than pure microcalcifications. This has implications for pre-operative assessment and surgical management. |
Keywords: | Carcinoma Cytology Mammography Core biopsy DCIS Breast cancer screening |
Description: | Crown copyright © 2006 Published by Elsevier Ltd. |
DOI: | 10.1016/j.breast.2006.08.003 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/623010/description#description |
Published version: | http://dx.doi.org/10.1016/j.breast.2006.08.003 |
Appears in Collections: | Aurora harvest Surgery publications |
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