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https://hdl.handle.net/2440/42274
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dc.contributor.author | Finch, G. | - |
dc.contributor.author | Fosh, B. | - |
dc.contributor.author | Anthony, A. | - |
dc.contributor.author | Texler, M. | - |
dc.contributor.author | Pearson, S. | - |
dc.contributor.author | Dennison, A. | - |
dc.contributor.author | Maddern, G. | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Journal of Surgical Research, 2004; 120(2):272-277 | - |
dc.identifier.issn | 0022-4804 | - |
dc.identifier.issn | 1095-8673 | - |
dc.identifier.uri | http://hdl.handle.net/2440/42274 | - |
dc.description | Copyright © 2004 Elsevier Inc. All rights reserved. | - |
dc.description.abstract | Background: The use of direct current electrolysis as a local nonthermal ablative technique for colorectal liver metastases promises to be a simple, safe, and effective therapy. Under general anesthesia, electrolysis is presently limited to tumors smaller than 5 cm, due to the protracted nature of its administration. In an attempt to enhance the effect of electrolysis, a direct current was passed through a preinjected bolus of acetic acid. Methods: The effect of a combination of electrolysis and an injection of acetic acid was tested in the liver of eight normal pigs. The volumes of necrosis caused were analyzed. Results: Acetic acid independently produced a volume of necrosis but did not provide a volumetric or rate advantage when used in combination with a direct current. Statistically, the only main effect on the volume of necrosis was a result of electrolysis. Conclusion: The use of 50% acetic acid to augment the efficacy of direct current electrolysis cannot be recommended. | - |
dc.description.statementofresponsibility | J. Guy Finch, Beverley G. Fosh, Adrian A. Anthony, Michael Texler, Susan Pearson, Ashley R. Dennison and Guy J. Maddern | - |
dc.description.uri | http://www.elsevier.com/wps/find/journaldescription.cws_home/622901/description#description | - |
dc.language.iso | en | - |
dc.publisher | Academic Press Inc Elsevier Science | - |
dc.source.uri | http://dx.doi.org/10.1016/j.jss.2004.03.019 | - |
dc.subject | Acetic acid | - |
dc.subject | colorectal liver metastases | - |
dc.subject | electrochemical therapy | - |
dc.subject | electrolysis | - |
dc.subject | porcine model | - |
dc.title | The use of a “Liquid” electrode in hepatic electrolysis | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.jss.2004.03.019 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Maddern, G. [0000-0003-2064-181X] | - |
Appears in Collections: | Aurora harvest 6 Surgery publications |
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