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https://hdl.handle.net/2440/43778
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Type: | Journal article |
Title: | Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors |
Author: | Hill, A. Buckley, J. Murphy, K. Howe, P. |
Citation: | American Journal of Clinical Nutrition, 2007; 85(5):1267-1274 |
Publisher: | Amer Soc Clinical Nutrition |
Issue Date: | 2007 |
ISSN: | 0002-9165 1938-3207 |
Statement of Responsibility: | Alison M Hill, Jonathan D Buckley, Karen J Murphy and Peter RC Howe |
Abstract: | <h4>Background</h4>Regular exercise and consuming long-chain n-3 fatty acids (FAs) from fish or fish oil can independently improve cardiovascular and metabolic health, but combining these lifestyle modifications may be more effective than either treatment alone.<h4>Objective</h4>We examined the individual and combined effects of n-3 FA supplements and regular exercise on body composition and cardiovascular health.<h4>Design</h4>Overweight volunteers [body mass index (BMI; in kg/m(2)): >25] with high blood pressure, cholesterol, or triacylglycerols were randomly assigned to one of the following interventions: fish oil (FO), FO and exercise (FOX), sunflower oil (SO; control), or SO and exercise (SOX). Subjects consumed 6 g tuna FO/d ( approximately 1.9 g n-3 FA) or 6 g SO/d. The exercise groups walked 3 d/wk for 45 min at 75% age-predicted maximal heart rate. Plasma lipids, blood pressure, and arterial function were assessed at 0, 6, and 12 wk. Body composition was assessed by dual-energy X-ray absorptiometry at 0 and 12 wk only.<h4>Results</h4>FO supplementation lowered triacylglycerols, increased HDL cholesterol, and improved endothelium-dependent arterial vasodilation (P<0.05). Exercise improved arterial compliance (P<0.05). Both fish oil and exercise independently reduced body fat (P<0.05).<h4>Conclusions</h4>FO supplements and regular exercise both reduce body fat and improve cardiovascular and metabolic health. Increasing intake of n-3 FAs could be a useful adjunct to exercise programs aimed at improving body composition and decreasing cardiovascular disease risk. |
Keywords: | n–3 Fatty acids body fat flow-mediated dilatation lipids dual-energy X-ray absorptiometry DXA |
Description: | © 2007 American Society for Nutrition |
DOI: | 10.1093/ajcn/85.5.1267 |
Published version: | http://www.ajcn.org/cgi/content/abstract/85/5/1267 |
Appears in Collections: | Aurora harvest 6 Molecular and Biomedical Science publications |
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