Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/44161
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DC Field | Value | Language |
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dc.contributor.author | Nordin, B. | - |
dc.contributor.author | Baghurst, P. | - |
dc.contributor.author | Metcalfe, A. | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | Calcified Tissue International, 2007; 80(6):349-352 | - |
dc.identifier.issn | 0171-967X | - |
dc.identifier.issn | 1432-0827 | - |
dc.identifier.uri | http://hdl.handle.net/2440/44161 | - |
dc.description | The original publication can be found at www.springerlink.com | - |
dc.description.abstract | The relation between fracture risk and bone density is frequently defined in terms of a relative hazard derived from the Cox proportional hazards model. The relative hazard is a multiplicative factor representing the rise in hazard for each standard deviation fall in bone mineral density, which has a typical value of about 1.5. It is not generally appreciated that this hazard may only be equated with absolute risk when risk is very low; at higher risk and over long periods, it is inappropriate to apply a multiplicative factor to absolute risk because risk has a range of 0-1 and cannot exceed unity. Here, we show how “hazard” can be converted to risk and how misleading the current practice of equating relative hazards with relative risks can be. | - |
dc.description.statementofresponsibility | B. E. Christopher Nordin, Peter A. Baghurst and Andrew Metcalfe | - |
dc.language.iso | en | - |
dc.publisher | Springer | - |
dc.source.uri | http://www.springerlink.com/content/u033206361025817/ | - |
dc.subject | Fracture risk | - |
dc.subject | Relative hazard | - |
dc.subject | Bone density | - |
dc.title | The difference between hazard and risk in the relation between bone density and fracture | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1007/s00223-007-9022-4 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Metcalfe, A. [0000-0002-7680-3577] | - |
Appears in Collections: | Aurora harvest Environment Institute publications Mathematical Sciences publications |
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