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https://hdl.handle.net/2440/51086
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Type: | Journal article |
Title: | The effect of CPP-ACP on enamel wear under severe erosive conditions |
Author: | Ranjitkar, S. Kaidonis, J. Richards, L. Townsend, G. |
Citation: | Archives of Oral Biology, 2009; 54(6):527-532 |
Publisher: | Pergamon-Elsevier Science Ltd |
Issue Date: | 2009 |
ISSN: | 0003-9969 1879-1506 |
Statement of Responsibility: | Sarbin Ranjitkar, John A. Kaidonis, Lindsay C. Richards and Grant C. Townsend |
Abstract: | <h4>Objective</h4>In addition to its role as a remineralizing agent in preventing dental caries, recent evidence has shown that casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) can protect teeth against erosion. The aim of this study was to determine whether CPP-ACP could reduce enamel wear rates under severe erosive conditions simulating heavy attrition and gastric regurgitation.<h4>Design</h4>Enamel specimens were subjected to 10,000 wear cycles at a load of 100 N and pH 1.2 in a tooth wear machine. The machine was stopped every 2 min (160 cycles), and CPP-ACP in the form of a paste was applied for 5 min in experimental group 1. A paste with the same formulation but without CPP-ACP was applied in experimental group 2. No paste was applied in the control group.<h4>Results</h4>A linear mixed model analysis indicated that the mean wear rates in experimental group 1 (0.44+/-0.05 mm(3) per 1000 cycles) and in experimental group 2 (0.63+/-0.06 mm(3) per 1000 cycles) were significantly lower than that in the control group (0.92+/-0.11 mm(3) per 1000 cycles) (p<0.05). The mean wear rate in experimental group 1 was also lower than that in experimental group 2 (p<0.05). Wear facets in experimental groups 1 and 2 were noted to be smoother and more polished than those in the control group.<h4>Conclusions</h4>Both remineralizing and lubricating properties of the paste containing CPP-ACP appear to contribute to wear reduction in enamel. These findings may lead to new strategies for the clinical management of tooth wear. |
Keywords: | Dental Enamel Humans Tooth Attrition Tooth Erosion Hydrochloric Acid Caseins Cariostatic Agents Materials Testing Hydrogen-Ion Concentration Time Factors |
Description: | Copyright © 2009 Elsevier Ltd All rights reserved. |
DOI: | 10.1016/j.archoralbio.2009.03.006 |
Description (link): | http://www.elsevier.com/wps/find/journaldescription.cws_home/203/description#description |
Published version: | http://dx.doi.org/10.1016/j.archoralbio.2009.03.006 |
Appears in Collections: | Aurora harvest Dentistry publications |
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