Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/51816
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | D-Leu-L-Phe-containing dipeptide inhibitors of -chymosrypsin- the role of the N- and C-termini in enzyme affinity |
Author: | Pearson, D. Abell, A. |
Citation: | ARKIVOC, 2008; 2008(12):85-93 |
Publisher: | Arkat USA, Inc. |
Issue Date: | 2008 |
ISSN: | 1551-7004 1551-7012 |
Statement of Responsibility: | David Pearson and Andrew D. Abell |
Abstract: | Three new compounds (3-5) based on a dipeptide non-covalent inhibitor (1) of α-chymotrypsin have been synthesised and assayed against the serine protease α-chymotrypsin. The stability of the compounds to α-chymotrypsin catalysed hydrolysis has been measured. All three compounds were inactive with a retained stability to enzyme catalysed hydrolysis. |
Keywords: | Chymotrypsin enzyme inhibitors peptidomimetics azobenzene |
DOI: | 10.3998/ark.5550190.0009.c10 |
Published version: | http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/2008/12/ |
Appears in Collections: | Aurora harvest Chemistry and Physics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.