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https://hdl.handle.net/2440/53724
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Type: | Journal article |
Title: | Cognitive effects of polyunsaturated fatty acids in children with attention deficit hyperactivity disorder symptoms: a randomised controlled trial |
Author: | Sinn, N. Bryan, J. Wilson, C. |
Citation: | Prostaglandins, Leukotrienes and Essential Fatty Acids, 2008; 78(4-5):311-326 |
Publisher: | Churchill Livingstone |
Issue Date: | 2008 |
ISSN: | 0952-3278 1532-2823 |
Statement of Responsibility: | N. Sinn, J. Bryan and C. Wilson |
Abstract: | This study investigated effects of PUFA and micronutrient supplementation on cognition in children with ADHD symptoms. In a randomised controlled trial, 7–12-year-old children with symptoms 2 S.D. on Conners’ ADHD Index were given PUFA, PUFA+multivitamins/minerals (MVM), or placebo for 15 weeks, and then all children were given PUFA+MVM for an additional 15 weeks. After 15 weeks there were improvements in a test of the ability to switch and control attention (Creature Counting) in the PUFA groups compared to placebo (N=129, p=0.002). This improvement was also observed in the placebo group after taking PUFA from weeks 16 to 30 (N=104). There were no significant improvements in other cognitive measures, or with additional micronutrient supplementation. However, improvements in cognitive performance mediated previous parent-reported improvements in inattention, hyperactivity and impulsivity [N. Sinn, J. Bryan, Effect of supplementation with polyunsaturated fatty acids and micronutrients on ADHD-related problems with attention and behaviour, J. Dev. Behav. Pediatr. 28 (2) (2007) 82–91], suggestive of a common neurological mechanism for these symptoms. |
Keywords: | Humans Fatty Acids, Unsaturated Follow-Up Studies Cognition Attention Deficit Disorder with Hyperactivity Child |
Description: | Copyright © 2008 Elsevier Ltd All rights reserved. |
DOI: | 10.1016/j.plefa.2008.04.004 |
Published version: | http://dx.doi.org/10.1016/j.plefa.2008.04.004 |
Appears in Collections: | Aurora harvest 5 Psychology publications |
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