Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/55643
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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Myer, L. | en |
dc.contributor.author | Wilkinson, David | en |
dc.contributor.author | Lombard, Carl | en |
dc.contributor.author | Zuma, Khangelani | en |
dc.contributor.author | Rotchford, Karen | en |
dc.contributor.author | Karim, S. S. Abdool | en |
dc.date.issued | 2003 | en |
dc.identifier.citation | Sexually Transmitted Infections, 2003; 79(3):208-213 | en |
dc.identifier.issn | 1368-4973 | en |
dc.identifier.uri | http://hdl.handle.net/2440/55643 | - |
dc.description | Copyright © 2007 by the BMJ Publishing Group Ltd. | en |
dc.description.abstract | Background: Syphilis remains a significant cause of preventable perinatal death in developing countries, with many women remaining untested and thus untreated. Syphilis testing in the clinic (on-site testing) may be a useful strategy to overcome this. We studied the impact of on-site syphilis testing on treatment delays and rates, and perinatal mortality. Methods: We conducted a cluster randomised controlled trial among seven pairs of primary healthcare clinics in rural South Africa, comparing on-site testing complemented by laboratory confirmation versus laboratory testing alone. Intervention clinics used the on-site test conducted by primary care nurses, with results and treatment available within an hour. Control clinics sent blood samples to the provincial laboratory, with results returned 2 weeks later. Results: Of 7134 women seeking antenatal care with available test results, 793 (11.1%) tested positive for syphilis. Women at intervention clinics completed treatment 16 days sooner on average (95% confidence interval: 11 to 21), though there was no significant difference in the proportion receiving adequate treatment at intervention (64%) and control (69%) clinics. There was also no significant difference in the proportion experiencing perinatal loss (3.3% v 5.1%; adjusted risk difference: −0.9%; 95% CI −4.4 to 2.7). Conclusions: Despite reducing treatment delays, the addition of on-site syphilis testing to existing laboratory testing services did not lead to higher treatment rates or reduce perinatal mortality. However on-site testing for syphilis may remain an important option for improving antenatal care in settings where laboratory facilities are not available. | en |
dc.language.iso | en | en |
dc.publisher | British Med Journal Publ Group | en |
dc.title | Impact of on-site testing for maternal syphilis on treatment delays, treatment rates, and perinatal mortality in rural South Africa: a randomised controlled trial | en |
dc.type | Journal article | en |
dc.contributor.school | Rural Clinical School | en |
dc.identifier.doi | 10.1136/sti.79.3.208 | en |
Appears in Collections: | Rural Clinical School publications |
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hdl_55643.pdf | 507.29 kB | Publisher's PDF | View/Open |
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